در این مقاله علمی از ژورنال Frontiers چاپ 2019 اثر RNase کایمریک خاص بر مقاومت آنتی بیوتیکی بررسی شده است. دراین مقاله از محیط LB  کمپانی Condalab استفاده شده است.

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Testing a Human Antimicrobial RNase Chimera Against Bacterial Resistance

Guillem Prats-Ejarque, Jiarui Li†, Fatima Ait-Ichou†, Helena Lorente and Ester Boix*

  • Faculty of Biosciences, Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Barcelona, Spain

The emergence of bacterial resistance to the most commonly used  antibiotics encourages the design of novel antimicrobial drugs.  Antimicrobial proteins and peptides (AMPs) are the key players in host  innate immunity. They exert a rapid and multifaceted action that reduces  the development of bacterial adaptation mechanisms. Human antimicrobial  RNases belonging to the vertebrate specific RNase A superfamily  participate in the maintenance of tissue and body fluid sterility. Among  the eight human canonical RNases, RNase 3 stands out as the most  cationic and effective bactericidal protein against Gram-ne

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